Longevity and wellness intelligence · read honestly

Alex Demo

6 September 2026Read from your genotyping file

29 of 102

markers read

14 of 16 areas have at least one marker read

How to read this report

Colour tells you where you are

Each colour is one group of your biology. A colour never means good or bad. Other reports colour a result from green to red; this one does not, because a chip cannot grade you.

Cellular
Systems
Heart and metabolism
Nutrients
Activity
Panels

A small mark tells you where a result sits

On its own scale, never against other people. Notable means a well-established result with something you can do about it. Worth a look means a tendency worth knowing. Typical is the common result. Beneficial is a helpful one. Not read means we could not look.

Notable
Worth a look
Typical
Beneficial
Not read

A count tells you how much we could read

Every area says how many of its markers your chip actually read. Only an area that was read can say “nothing unusual”; the others say “we could not look”. Not seen is not the same as not there.

3 of 6 read · Methylation
a dashed ring: a marker was not read
typed on the chip
imputed

Where your signal sits

16 areas · 6 groups

Every area of your biology, in a fixed order. The mark and the word say where a result sits on its own scale; the bar says how many of the area’s markers your chip actually read — the pale part is what it could not. For the two screens the count is genes fully read. No colour means good or bad.

Cellular

Systems

Heart and metabolism

Nutrients

Activity

Panels

Your story

One spread for each group of your biology: what it is in plain words, what your own genotypes say, and what could not be read.

Cellular

4 areas

We are the sum of our cells. Inside each one the folate cycle recycles what the cell needs, detox enzymes clear what it does not, and the immune response and the ageing of the cell are set in part by common variants. Here, one area is notable, two are worth a look and one carries a helpful result.

MethylationNotable
Detox and histamineWorth a look
ImmunityWorth a look
LongevityBeneficial

Methylation

Notable3 of 6 read

Methylation is the cell’s way of switching things on and off and of recycling homocysteine. It runs on folate and B12, and a few genes set how fast the cycle turns.

On your file

Read on your file: MTHFR — mildly reduced MTHFR activity (~65%); usually benign with adequate folate. MTHFR — one 1298C allele; minimal effect alone. Not read: MTRR, MTR, CBS.

Keep folate-rich foods regular (leafy greens, legumes, citrus).

Blood tests for this area

Homocysteine none on file
Vitamin B12 none on file

MTHFR, MTRR, MTR, CBS, COMT · 3 of 6 read · MTRR, MTR, CBS not read

Gene	Variant	Your letters	How it was read	Where it sits	What it says
MTHFR★ the plan rests on this genotype	C677T (Ala222Val)rs1801133	AG	typed on the chip	Notable	MTHFR — mildly reduced MTHFR activity (~65%); usually benign with adequate folate.
MTHFR★ the plan rests on this genotype	A1298C (Glu429Ala)rs1801131	GT	typed on the chip	Worth a look	MTHFR — one 1298C allele; minimal effect alone. Read with your 677 result — a 677 + 1298 compound het retains ~50-60% activity.
MTRR	A66G (Ile22Met)rs1801394	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
MTR	A2756G (Asp919Gly)rs1805087	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
CBS	699C>T (transsulfuration)rs234706	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
COMT	Val158Metrs4680	AG	typed on the chip	Worth a look	COMT — intermediate COMT activity; indirect methylation link is small.

★ the plan rests on this genotype

Not read on this file: MTRR, MTR, CBS

Detox and histamine

Worth a look3 of 11 read

Detoxification is how the liver and cells neutralise what they do not need; histamine clearance sits beside it. Some of the best-known enzymes are read as present-or-deleted, which a chip cannot do.

On your file

Read on your file: COMT — intermediate COMT activity; indirect methylation link is small. GSTP1 — one 105Val allele; a modestly altered glutathione-conjugation profile. Not read: MAOA, GSTM1, NOS3, 4 more.

Cruciferous vegetables (broccoli, rocket, kale, Brussels sprouts) support phase-II glutathione conjugation

COMT, MAOA, GSTP1, GSTM1, NOS3 and 5 more · 3 of 11 read · MAOA, GSTM1, NOS3, 4 more not read

Gene	Variant	Your letters	How it was read	Where it sits	What it says
COMT	Val158Metrs4680	AG	typed on the chip	Worth a look	COMT — intermediate COMT activity; indirect methylation link is small.
MAOA	rs6323 (R297R, activity tag)rs6323	not read	not read	Not read	Not read — on chromosome X, which this file does not impute
GSTP1	Ile105Valrs1695	AG	typed on the chip	Worth a look	GSTP1 — one 105Val allele; a modestly altered glutathione-conjugation profile.
GSTM1	GSTM1 null (whole-gene deletion)GSTM1-null-CNV	not read	not read	Not read	Not read — an insertion or deletion — not on arrays
NOS3	Glu298Asp (eNOS)rs1799983	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
PEMT	rs7946 (V175M)rs7946	CT	typed on the chip	Worth a look	PEMT — one T allele; a modestly higher dietary-choline demand (eggs/liver/soy lecithin).
AOC1	DAO rs10156191 (Thr16Met)rs10156191	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
AOC1	DAO rs1049793 (His645Asp)rs1049793	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
SOD2	Ala16Val (mitochondrial targeting)rs4880	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
GPX1	Pro198Leurs1050450	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
NQO1	Pro187Serrs1800566	not read	not read	Not read	Not read — not on this chip; not imputable with confidence

Not read on this file: MAOA, GSTM1, NOS3, AOC1, SOD2, GPX1, NQO1

Immunity

Worth a look1 of 5 read

Inflammation is the immune system’s first response; a few common variants nudge how strong it tends to be. A blood test says far more about inflammation than these genes.

On your file

Read on your file: TNF — one -308A allele; a modestly higher TNF-α inflammatory-tone tendency (inconsistent). Not read on this chip: HLA-DQA1, PTPN22, CTLA4, 1 more — drawn as a gap, never as a clean result.

A regular CRP would say more — none on file.

Blood tests for this area

CRP none on file

HLA-DQA1, PTPN22, CTLA4, IL6, TNF · 1 of 5 read · HLA-DQA1, PTPN22, CTLA4, 1 more not read

Gene	Variant	Your letters	How it was read	Where it sits	What it says
HLA-DQA1	HLA-DQ2.5 tag (rs2187668)rs2187668	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
PTPN22	R620W (Arg620Trp)rs2476601	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
CTLA4	CT60 (rs3087243, 3')rs3087243	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
IL6	-174 G>C (promoter)rs1800795	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
TNF	-308 G>A (promoter, TNF2)rs1800629	AG	typed on the chip	Worth a look	TNF — one -308A allele; a modestly higher TNF-α inflammatory-tone tendency (inconsistent).

Not read on this file: HLA-DQA1, PTPN22, CTLA4, IL6

Longevity

Beneficial2 of 5 read

A few common variants are found more often in people who live very long. Context, not a promise; nothing in daily life follows from them.

On your file

Read on your file: FOXO3 — two longevity-associated alleles; favourable-leaning (replicated in centenarian cohorts). KLOTHO KL-VS heterozygote — the favourable-leaning configuration (heterozygote advantage); modest. Not read: APOE, SIRT1, TP53.

APOE, FOXO3, KLOTHO, SIRT1, TP53 · 2 of 5 read · APOE, SIRT1, TP53 not read

Gene	Variant	Your letters	How it was read	Where it sits	What it says
APOE	ε4-defining SNP (with rs7412 → ε2/ε3/ε4)rs429358	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
FOXO3	rs2802292 (intron 2)rs2802292	GG	typed on the chip	Beneficial	FOXO3 — two longevity-associated alleles; favourable-leaning (replicated in centenarian cohorts) — an odds nudge, not a guarantee.
KLOTHO	KL-VS (Phe352Val)rs9536314	GT	typed on the chip	Beneficial	KLOTHO KL-VS heterozygote — the favourable-leaning configuration (heterozygote advantage); modest, replicated.
SIRT1	rs7069102 (intron)rs7069102	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
TP53	R72P (Arg72Pro)rs1042522	not read	not read	Not read	Not read — not on this chip; not imputable with confidence

Not read on this file: APOE, SIRT1, TP53

Systems

5 areas

The systems group is where signals travel between organs: the hormones, the brain’s chemistry, the body clock, the senses and the skin. Where a watch has measured something, the measurement is what the app acts on. Here, five are worth a look.

HormonesWorth a look
Mood and focusWorth a look
Sleep and body clockWorth a look
SensesWorth a look
Skin and hairWorth a look

Hormones

Worth a look1 of 7 read

Hormones are the body’s slow messages; a few enzymes make and clear them, and common variants set how fast they work.

On your file

Read on your file: ESR1 — one 'P' allele; a small ESR1-sensitivity tendency (read with XbaI). Not read on this chip: AR, SRD5A2, CYP19A1, 2 more — drawn as a gap, never as a clean result.

AR, SRD5A2, CYP19A1, ESR1, SHBG · 1 of 7 read · AR, SRD5A2, CYP19A1, 2 more not read

Gene	Variant	Your letters	How it was read	Where it sits	What it says
AR	AR CAG repeat (polyQ length)AR-CAG-repeat	not read	not read	Not read	Not read — a repeat length, not a single site — needs a dedicated assay
SRD5A2	V89L (Val89Leu)rs523349	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
CYP19A1	rs10046 (3'-UTR, aromatase)rs10046	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
CYP19A1	rs700518 (Val80, synonymous)rs700518	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
ESR1	PvuII (rs2234693, intron 1)rs2234693	CT	typed on the chip	Worth a look	ESR1 — one 'P' allele; a small ESR1-sensitivity tendency (read with XbaI).
ESR1	XbaI (rs9340799, intron 1)rs9340799	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
SHBG	D356N (Asp356Asn)rs6259	not read	not read	Not read	Not read — not on this chip; not imputable with confidence

Not read on this file: AR, SRD5A2, CYP19A1, ESR1 (1 of 2 markers), SHBG

Mood and focus

Worth a look2 of 5 read

The brain clears its own messengers with a handful of enzymes, and caffeine borrows the same wiring. These are tendencies of temperament, never a diagnosis.

On your file

Read on your file: COMT — intermediate COMT activity; indirect methylation link is small. Not read on this chip: MAOA, SLC6A4, FKBP5 — drawn as a gap, never as a clean result.

COMT, MAOA, SLC6A4, BDNF, FKBP5 · 2 of 5 read · MAOA, SLC6A4, FKBP5 not read

Gene	Variant	Your letters	How it was read	Where it sits	What it says
COMT	Val158Metrs4680	AG	typed on the chip	Worth a look	COMT — intermediate COMT activity; indirect methylation link is small.
MAOA	rs6323 (R297R, activity tag)rs6323	not read	not read	Not read	Not read — on chromosome X, which this file does not impute
SLC6A4	5-HTTLPR (promoter L/S indel; rs25531 partial tag)rs25531	not read	not read	Not read	Not read — an insertion or deletion — not on arrays
BDNF	Val66Metrs6265	CC	typed on the chip	Typical	BDNF — the common genotype; normal activity-dependent BDNF secretion.
FKBP5	rs1360780 (intron 2)rs1360780	not read	not read	Not read	Not read — not on this chip; not imputable with confidence

Not read on this file: MAOA, SLC6A4, FKBP5

Sleep and body clock

Worth a look1 of 5 read

The clock genes set a tendency to be early or late. A watch measures what the genes only lean toward, so the measurement always outranks the genotype.

On your file

Read on your file: CLOCK — one eveningness-leaning allele (a modest, inconsistent tendency). Not read on this chip: PER3, CRY1, BHLHE41, 1 more — drawn as a gap, never as a clean result.

One eveningness-leaning allele (a modest, inconsistent signal).

PER3, CLOCK, CRY1, BHLHE41, MTNR1B · 1 of 5 read · PER3, CRY1, BHLHE41, 1 more not read

Gene	Variant	Your letters	How it was read	Where it sits	What it says
PER3	PER3 VNTR (4/5-repeat)rs57875989	not read	not read	Not read	Not read — a repeat length, not a single site — needs a dedicated assay
CLOCK	3111T>C (3'-UTR)rs1801260	AG	typed on the chip	Worth a look	CLOCK — one eveningness-leaning allele (a modest, inconsistent tendency).
CRY1	rs2287161 (intron)rs2287161	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
BHLHE41	DEC2 P385R (Pro385Arg)rs121912617	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
MTNR1B	rs10830963 (intron)rs10830963	not read	not read	Not read	Not read — not on this chip; not imputable with confidence

Not read on this file: PER3, CRY1, BHLHE41, MTNR1B

Senses

Worth a look1 of 7 read

Taste and smell are the most directly inherited things a chip can see, and the least consequential. A taste trait is a trait, never a risk.

On your file

Read on your file: TAS2R38 — one taster (PAV) allele at position 49 (intermediate); read with two other TAS2R38 markers. Not read on this chip: CYP2D6, TAS2R38 (2 of 3 markers), OR6A2, 2 more — drawn as a gap, never as a clean result.

CYP2D6, TAS2R38, OR6A2, OPRM1, SCN9A · 1 of 7 read · CYP2D6, TAS2R38 (2 of 3 markers), OR6A2, 2 more not read

Gene	Variant	Your letters	How it was read	Where it sits	What it says
CYP2D6	CYP2D6 activity (star-allele diplotype)CYP2D6-star-alleles	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
TAS2R38	A49P (bitter-taste diplotype 1/3)rs713598	CG	typed on the chip	Worth a look	TAS2R38 — one taster (PAV) allele at position 49 (intermediate); read with two other TAS2R38 markers.
TAS2R38	V262A (bitter-taste diplotype 2/3)rs1726866	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
TAS2R38	I296V (bitter-taste diplotype 3/3)rs10246939	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
OR6A2	rs6591536 (cilantro soapy-taste)rs6591536	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
OPRM1	A118G (Asn40Asp)rs1799971	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
SCN9A	R1150W (Arg1150Trp)rs6746030	not read	not read	Not read	Not read — not on this chip; not imputable with confidence

Not read on this file: CYP2D6, TAS2R38 (2 of 3 markers), OR6A2, OPRM1, SCN9A

Skin and hair

Worth a look1 of 6 read

Collagen, pigmentation and repair carry a few common variants; sun and sleep do more for skin than any of them.

On your file

Read on your file: HERC2 — one blue-eye/lighter allele (intermediate; a green/hazel or variable-eye leaning). Not read on this chip: MC1R, SLC45A2, FLG, 1 more — drawn as a gap, never as a clean result.

MC1R, SLC45A2, HERC2, FLG, MMP1 · 1 of 6 read · MC1R, SLC45A2, FLG, 1 more not read

Gene	Variant	Your letters	How it was read	Where it sits	What it says
MC1R	R151C (Arg151Cys)rs1805007	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
MC1R	R160W (Arg160Trp)rs1805008	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
SLC45A2	L374F (Leu374Phe)rs16891982	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
HERC2	rs12913832 (OCA2 regulator)rs12913832	AG	typed on the chip	Worth a look	HERC2 — one blue-eye/lighter allele (intermediate; a green/hazel or variable-eye leaning).
FLG	R501X (Arg501Ter)rs61816761	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
MMP1	-1607 1G/2G (promoter insertion)rs1799750	not read	not read	Not read	Not read — an insertion or deletion — not on arrays

Not read on this file: MC1R, SLC45A2, FLG, MMP1

Heart and metabolism

2 areas

The heart group is where blood lipids, blood sugar and liver fat are read. It is the smallest group and the one where measured values matter most, because they stand next to the genes — and outrank them. Here, one area is notable and one reads as the common result.

Heart and lipidsTypical
Blood sugar and liverNotable

Heart and lipids

Typical1 of 3 read

Blood fats travel in particles, and a handful of genes set how they are made and cleared. Common variants lean the levels; food, weight and age do the rest — and a blood value outranks every gene here.

On your file

The one marker read here shows the common result — nothing asks for attention. Not read on this chip: APOE, LPA (1 of 2 markers) — drawn as a gap, never as a clean result. Your last LDL was 3.4 mmol/L (May 2025), against a lab range of < 3.

Blood tests for this area

LDL 3.4 mmol/L · 2025-05-19
ApoB none on file
Lp(a) none on file

APOE, LPA · 1 of 3 read · APOE, LPA (1 of 2 markers) not read

Gene	Variant	Your letters	How it was read	Where it sits	What it says
APOE	ε4-defining SNP (with rs7412 → ε2/ε3/ε4)rs429358	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
LPA	rs10455872 (Lp(a) tag)rs10455872	AA	typed on the chip	Typical	LPA — no high-Lp(a) tag allele (but this does not rule out high Lp(a) — measure serum Lp(a)).
LPA	rs3798220 (I4399M, Lp(a) tag)rs3798220	not read	not read	Not read	Not read — a repeat length, not a single site — needs a dedicated assay

Not read on this file: APOE, LPA (1 of 2 markers)

Blood sugar and liver

Notable2 of 5 read

A few common variants nudge how the body handles sugar and stores fat in the liver. A glucose or HbA1c value says more than all of them together.

On your file

Read on your file: TCF7L2 — one T2D-risk allele; a modestly raised polygenic T2D tendency — read against glucose/HbA1c. FTO — one adiposity allele; a modestly increased appetite/adiposity predisposition (small effect). Not read: MC4R, PNPLA3, TM6SF2. Your last HbA1c was 5.3 % (May 2025).

The most established common type-2-diabetes variant — and highly modifiable.

Blood tests for this area

HbA1c 5.3 % · 2025-05-19
Fasting glucose none on file

TCF7L2, FTO, MC4R, PNPLA3, TM6SF2 · 2 of 5 read · MC4R, PNPLA3, TM6SF2 not read

Gene	Variant	Your letters	How it was read	Where it sits	What it says
TCF7L2★ the plan rests on this genotype	rs7903146 (intron)rs7903146	CT	typed on the chip	Notable	TCF7L2 — one T2D-risk allele; a modestly raised polygenic T2D tendency — read against glucose/HbA1c.
FTO★ the plan rests on this genotype	rs9939609 (intron 1)rs9939609	AT	typed on the chip	Notable	FTO — one adiposity allele; a modestly increased appetite/adiposity predisposition (small effect).
MC4R	rs17782313 (near MC4R)rs17782313	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
PNPLA3	I148Mrs738409	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
TM6SF2	E167Krs58542926	not read	not read	Not read	Not read — not on this chip; not imputable with confidence

★ the plan rests on this genotype

Not read on this file: MC4R, PNPLA3, TM6SF2

The blood test behind the finding

LDL, mmol/L

LDL, mmol/L, three draws against a common target line; dashed between draws because nothing was measured in between. This number outranks every gene on the page.

Nutrients

2 areas

The nutrients group is where the plate meets the genome: lactose, caffeine, folate, iron, the vitamins, and what the gut does with them. Nothing on this page is a diet — no macro split, no grams, no supplement dose. Here, two are worth a look.

Food and vitaminsWorth a look
Gut and digestionWorth a look

Food and vitamins

Worth a look7 of 23 read

Whether milk sits well, how coffee lands, how much of a vitamin you absorb: a few common variants set these tendencies. Nothing here is a diet.

On your file

Read on your file: FTO — Modestly increased appetite/adiposity predisposition. MTHFR — Mildly reduced MTHFR activity — usually benign with adequate folate. Four more markers carry a smaller or thinner-evidence effect. Not read on this chip: ALDH2, ADH1B, CYP1A2, 7 more — drawn as a gap, never as a clean result.

25-hydroxy vitamin D and ferritin would say more — none on file.

Blood tests for this area

Vitamin D none on file
Vitamin B12 none on file
Ferritin none on file

MCM6/LCT, FTO, MTHFR, FUT2, TAS2R38 and 8 more · 7 of 23 read · ALDH2, ADH1B, CYP1A2, 7 more not read

Gene	Variant	Your letters	How it was read	Where it sits	What it says
MCM6/LCT	Lactose tolerancers4988235	GG	typed on the chip	Typical	MCM6/LCT — Lactase non-persistent genotype — adult lactose intolerance is more likely; symptoms vary.
FTO★ the plan rests on this genotype	Appetite / obesity predispositionrs9939609	AT	typed on the chip	Worth a look	FTO — Modestly increased appetite/adiposity predisposition.
MTHFR★ the plan rests on this genotype	Folate metabolism (C677T)rs1801133	AG	typed on the chip	Worth a look	MTHFR — Mildly reduced MTHFR activity — usually benign with adequate folate.
MTHFR★ the plan rests on this genotype	Folate metabolism (A1298C)rs1801131	GT	typed on the chip	Worth a look	MTHFR — minimal effect alone; a 677 + 1298 compound heterozygote retains ~50–60% MTHFR activity (PMC5778916).
FUT2	Vitamin B12 status (secretor)rs602662	AG	typed on the chip	Worth a look	FUT2 — Intermediate secretor status.
TAS2R38	Bitter taste (PTC/PROP)rs713598	CG	typed on the chip	Worth a look	TAS2R38 — Intermediate bitter taster.
COMT	Catecholamine/dopamine clearance (Val158Met)rs4680	AG	typed on the chip	Worth a look	COMT — Intermediate COMT activity (Val/Met).
ALDH2	Alcohol flush (acetaldehyde clearance)rs671	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
ADH1B	Alcohol metabolism speedrs1229984	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
CYP1A2	Caffeine metabolism — inducibility, not baseline raters762551	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
ADORA2A	Caffeine sensitivity / anxietyrs5751876	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
FTO	Appetite / adiposity (causal FTO variant)rs1421085	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
BCMO1	Beta-carotene → vitamin A conversionrs12934922	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
TAS2R38	Bitter-taste haplotype (Val262Ala)rs1726866	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
TAS2R38	Bitter-taste haplotype (Ile296Val)rs10246939	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
HFE	Iron overload (C282Y)rs1800562	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
HFE	Iron handling (H63D)rs1799945	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
HFE	Iron handling (S65C)rs1800730	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
COMT	COMT haplotype (His62His, linked to Val158Met)rs4633	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
VDR	Vitamin-D receptor (FokI)rs2228570	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
VDR	Vitamin-D receptor (BsmI)rs1544410	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
VDR	Vitamin-D receptor (TaqI)rs731236	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
VDR	Vitamin-D receptor (ApaI)rs7975232	not read	not read	Not read	Not read — not on this chip; not imputable with confidence

★ the plan rests on this genotype

Not read on this file: ALDH2, ADH1B, CYP1A2, ADORA2A, FTO (1 of 2 markers), BCMO1, TAS2R38 (2 of 3 markers), HFE, COMT (1 of 2 markers), VDR

Gut and digestion

Worth a look2 of 8 read

The gut’s genes are mostly about what it can break down and which microbes it hosts.

On your file

Read on your file: FUT2 — one non-secretor-tag allele (read with another FUT2 marker; non-secretor status is recessive). Not read on this chip: FUT2 (1 of 2 markers), AOC1, HLA-DQA1, 1 more — drawn as a gap, never as a clean result.

You likely produce little lactase in adulthood, so dairy may cause bloating or discomfort.

Blood tests for this area

Vitamin B12 none on file

MCM6, FUT2, AOC1, HLA-DQA1, NOD2 · 2 of 8 read · FUT2 (1 of 2 markers), AOC1, HLA-DQA1, 1 more not read

Gene	Variant	Your letters	How it was read	Where it sits	What it says
MCM6	LCT -13910C>T (lactase persistence)rs4988235	GG	typed on the chip	Typical	MCM6 — the non-persistence genotype: a genetic lactase-non-persistence tendency (reduced adult lactose digestion). This is a tendency, not a diagnosis.
FUT2	W143X (secretor status)rs601338	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
FUT2	rs602662 (secretor tag)rs602662	AG	typed on the chip	Worth a look	FUT2 — one non-secretor-tag allele (read with another FUT2 marker; non-secretor status is recessive).
AOC1	DAO rs10156191 (Thr16Met)rs10156191	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
AOC1	DAO rs1049793 (His645Asp)rs1049793	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
HLA-DQA1	HLA-DQ2.5 tag (rs2187668)rs2187668	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
NOD2	R702W (Arg702Trp)rs2066844	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
NOD2	G908R (Gly908Arg)rs2066845	not read	not read	Not read	Not read — not on this chip; not imputable with confidence

Not read on this file: FUT2 (1 of 2 markers), AOC1, HLA-DQA1, NOD2

Activity

1 area

The activity group is one area, and it is where the market overreaches most: injury and endurance verdicts from three or four sites. Here the genes are listed with their gaps, and the numbers from a watch sit beside them, because those are the ones that move. Here, one area is notable.

Training and recoveryNotable

Training and recovery

Notable2 of 6 read

Fitness reports lead with a few genes for muscle fibre type and endurance. Most cannot be read on a chip, and the numbers from a watch are the ones that move.

On your file

Read on your file: ACTN3 — endurance-leaning; common in the general population, not a deficiency. Not read on this chip: ACE, PPARGC1A, COL5A1, 1 more — drawn as a gap, never as a clean result.

Endurance-leaning profile — you likely respond well to aerobic and higher-rep work.

ACTN3, ACE, PPARGC1A, COL1A1, COL5A1 and 1 more · 2 of 6 read · ACE, PPARGC1A, COL5A1, 1 more not read

Gene	Variant	Your letters	How it was read	Where it sits	What it says
ACTN3★ the plan rests on this genotype	R577Xrs1815739	TT	typed on the chip	Notable	ACTN3 — endurance-leaning; common in the general population, not a deficiency.
ACE	I/D (Alu indel)rs4646994	not read	not read	Not read	Not read — an insertion or deletion — not on arrays
PPARGC1A	Gly482Serrs8192678	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
COL1A1	Sp1 (+1245G>T)rs1800012	CC	typed on the chip	Typical	COL1A1 — the common COL1A1 Sp1 genotype (soft-tissue injury-risk axis).
COL5A1	rs12722 (3'-UTR)rs12722	not read	not read	Not read	Not read — not on this chip; not imputable with confidence
AMPD1	Gln12Ter (Q12X)rs17602729	not read	not read	Not read	Not read — not on this chip; not imputable with confidence

★ the plan rests on this genotype

Not read on this file: ACE, PPARGC1A, COL5A1, AMPD1

Measured by your wearable, not inherited

No watch data is on this record yet. When it arrives, this card carries your measured fitness and movement, and the training call comes from those numbers, never from a gene.

The genes cannot change those numbers; they can only say where a tendency might have come from.

Panels

2 areas

The two panels are screens, not wellness areas, and they come last for a reason: on a chip, “not read” is most of their story. They stay in the report so that a quiet result is never mistaken for a clean one. This report writes “not read” where laboratories write the common version by default.

Hereditary cancer screenNot read
MedicinesNot read

Your plan

6 things · 3 areas

6 things, each backed by a genotype that was actually read and by established or probable evidence. Where a list is empty it says so. We do not dose supplements from a chip; a supplement is a practitioner’s line and waits for a blood value.

Blood sugar and liver

Both markers read here carry a variant with an effect: TCF7L2, FTO. Your last HbA1c was 5.3 % (May 2025).

Eat

The most established common type-2-diabetes variant — and highly modifiable.

Live

A modest appetite/adiposity tendency that responds well to habit: protein-forward, high-satiety meals and regular activity blunt it.

Measure

Nothing here — no measured genotype in this area carries a rule for it.

Methylation

All three markers read here carry a variant with an effect: MTHFR, COMT.

Eat

Keep folate-rich foods regular (leafy greens, legumes, citrus).
Keep folate-rich foods regular; A1298C matters most in combination with C677T, so a varied, greens-forward diet keeps the folate cycle running…

Live

Nothing here — no measured genotype in this area carries a rule for it.

Measure

Homocysteine, with folate and B12 — none on file yet.

Training and recovery

One of the 2 markers read here carries a variant with an effect: ACTN3.

Eat

Nothing here — no measured genotype in this area carries a rule for it.

Live

Endurance-leaning profile — you likely respond well to aerobic and higher-rep work. This is a common, healthy variant, not a deficiency

Measure

Nothing here — no measured genotype in this area carries a rule for it.

Also supported · 3 more areas

Detox and histamine

Eat

Cruciferous vegetables (broccoli, rocket, kale, Brussels sprouts) support phase-II glutathione conjugation
Include choline-rich foods (eggs, legumes, cruciferous veg) — this variant lowers how much choline your body makes, so dietary choline covers the gap.

Sleep and body clock

Live

One eveningness-leaning allele (a modest, inconsistent signal).

Gut and digestion

Eat

You likely produce little lactase in adulthood, so dairy may cause bloating or discomfort.

Measure

Serum B12 or active B12 — none on file yet.

Your ticks are saved on this device only, in this browser. They are not sent to Indaga and do not change your plan.

Not on this file

73 markers · listed, never guessed

The markers this file could not read, and why. A quiet result means quiet at the sites that could be read, nothing more. Where a chip has no site, other laboratories write the common version by default; this report writes “not read”, so you can tell the two apart.

Methylation3 not read

Marker	What it is about	Why it was not read
MTRR A66G (Ile22Met)	B12-dependent remethylation	not on this chip; not imputable with confidence
MTR A2756G (Asp919Gly)	homocysteine remethylation	not on this chip; not imputable with confidence
CBS 699C>T (transsulfuration)	transsulfuration exit	not on this chip; not imputable with confidence

Detox and histamine8 not read

Marker	What it is about	Why it was not read
MAOA	monoamine degradation	on chromosome X, which this file does not impute
GSTM1	phase-II glutathione conjugation	an insertion or deletion — not on arrays
NOS3 Glu298Asp (eNOS)	endothelial nitric-oxide production	not on this chip; not imputable with confidence
AOC1 DAO rs10156191 (Thr16Met)	dietary-histamine degradation	not on this chip; not imputable with confidence
AOC1 DAO rs1049793 (His645Asp)	dietary-histamine degradation	not on this chip; not imputable with confidence
SOD2	mitochondrial antioxidant defence	not on this chip; not imputable with confidence
GPX1 Pro198Leu	selenium-dependent antioxidant defence	not on this chip; not imputable with confidence
NQO1 Pro187Ser	quinone detox / antioxidant recycling	not on this chip; not imputable with confidence

Immunity4 not read

Marker	What it is about	Why it was not read
HLA-DQA1 HLA-DQ2.5 tag (rs2187668)	HLA autoimmune risk haplotype	not on this chip; not imputable with confidence
PTPN22 R620W (Arg620Trp)	broad autoimmune risk	not on this chip; not imputable with confidence
CTLA4 CT60 (rs3087243, 3')	immune-checkpoint tone	not on this chip; not imputable with confidence
IL6 -174 G>C (promoter)	IL-6 inflammatory tone	not on this chip; not imputable with confidence

Longevity3 not read

Marker	What it is about	Why it was not read
APOE	APOE isoform	not on this chip; not imputable with confidence
SIRT1 rs7069102 (intron)	metabolic/aging signalling	not on this chip; not imputable with confidence
TP53 R72P (Arg72Pro)	longevity and cancer/apoptosis tradeoff	not on this chip; not imputable with confidence

Hormones6 not read

Marker	What it is about	Why it was not read
AR	androgen-receptor sensitivity	a repeat length, not a single site — needs a dedicated assay
SRD5A2 V89L (Val89Leu)	5α-reductase activity	not on this chip; not imputable with confidence
CYP19A1	aromatase activity	not on this chip; not imputable with confidence
CYP19A1	aromatase activity	not on this chip; not imputable with confidence
ESR1	estrogen-receptor-α sensitivity	not on this chip; not imputable with confidence
SHBG D356N (Asp356Asn)	sex-hormone-binding-globulin level	not on this chip; not imputable with confidence

Mood and focus3 not read

Marker	What it is about	Why it was not read
MAOA	monoamine degradation	on chromosome X, which this file does not impute
SLC6A4	serotonin-transporter expression	an insertion or deletion — not on arrays
FKBP5 rs1360780 (intron 2)	HPA-axis / cortisol stress reactivity	not on this chip; not imputable with confidence

Sleep and body clock4 not read

Marker	What it is about	Why it was not read
PER3 PER3 VNTR (4/5-repeat)	chronotype	a repeat length, not a single site — needs a dedicated assay
CRY1 rs2287161 (intron)	core-clock repression / sleep timing	not on this chip; not imputable with confidence
BHLHE41 DEC2 P385R (Pro385Arg)	familial natural short sleep	not on this chip; not imputable with confidence
MTNR1B rs10830963 (intron)	melatonin-receptor signalling	not on this chip; not imputable with confidence

Senses6 not read

Marker	What it is about	Why it was not read
CYP2D6	analgesic activation / drug metabolism —	not on this chip; not imputable with confidence
TAS2R38	bitter taste — TAS2R38 PAV/AVI diplotype	not on this chip; not imputable with confidence
TAS2R38	bitter taste — TAS2R38 PAV/AVI diplotype	not on this chip; not imputable with confidence
OR6A2	cilantro 'soapy' aldehyde perception —	not on this chip; not imputable with confidence
OPRM1 A118G (Asn40Asp)	pain sensitivity / opioid response	not on this chip; not imputable with confidence
SCN9A R1150W (Arg1150Trp)	pain sensitivity	not on this chip; not imputable with confidence

Skin and hair5 not read

Marker	What it is about	Why it was not read
MC1R R151C (Arg151Cys)	red-hair / fair-skin / UV sensitivity	not on this chip; not imputable with confidence
MC1R R160W (Arg160Trp)	red-hair / fair-skin / UV sensitivity	not on this chip; not imputable with confidence
SLC45A2 L374F (Leu374Phe)	constitutive skin/hair pigmentation	not on this chip; not imputable with confidence
FLG R501X (Arg501Ter)	skin-barrier integrity / eczema	not on this chip; not imputable with confidence
MMP1	collagen remodelling / skin photoaging	an insertion or deletion — not on arrays

Heart and lipids2 not read

Marker	What it is about	Why it was not read
APOE	APOE isoform	not on this chip; not imputable with confidence
LPA	lipoprotein level	a repeat length, not a single site — needs a dedicated assay

Blood sugar and liver3 not read

Marker	What it is about	Why it was not read
MC4R rs17782313 (near MC4R)	adiposity / satiety	not on this chip; not imputable with confidence
PNPLA3 I148M	hepatic fat / NAFLD progression	not on this chip; not imputable with confidence
TM6SF2 E167K	hepatic fat / NAFLD	not on this chip; not imputable with confidence

Food and vitamins16 not read

Marker	What it is about	Why it was not read
ALDH2	Alcohol flush	not on this chip; not imputable with confidence
ADH1B Alcohol metabolism speed	Alcohol metabolism speed	not on this chip; not imputable with confidence
CYP1A2	Caffeine metabolism — inducibility, not	not on this chip; not imputable with confidence
ADORA2A	Caffeine sensitivity / anxiety	not on this chip; not imputable with confidence
FTO	Appetite / adiposity	not on this chip; not imputable with confidence
BCMO1	Beta-carotene to vitamin A conversion	not on this chip; not imputable with confidence
TAS2R38	Bitter-taste haplotype	not on this chip; not imputable with confidence
TAS2R38	Bitter-taste haplotype	not on this chip; not imputable with confidence
HFE Iron overload (C282Y)	Iron overload	not on this chip; not imputable with confidence
HFE Iron handling (H63D)	Iron handling	not on this chip; not imputable with confidence
HFE Iron handling (S65C)	Iron handling	not on this chip; not imputable with confidence
COMT	COMT haplotype	not on this chip; not imputable with confidence
VDR Vitamin-D receptor (FokI)	Vitamin-D receptor	not on this chip; not imputable with confidence
VDR Vitamin-D receptor (BsmI)	Vitamin-D receptor	not on this chip; not imputable with confidence
VDR Vitamin-D receptor (TaqI)	Vitamin-D receptor	not on this chip; not imputable with confidence
VDR Vitamin-D receptor (ApaI)	Vitamin-D receptor	not on this chip; not imputable with confidence

Gut and digestion6 not read

Marker	What it is about	Why it was not read
FUT2 W143X (secretor status)	secretor status	not on this chip; not imputable with confidence
AOC1 DAO rs10156191 (Thr16Met)	dietary-histamine degradation	not on this chip; not imputable with confidence
AOC1 DAO rs1049793 (His645Asp)	dietary-histamine degradation	not on this chip; not imputable with confidence
HLA-DQA1 HLA-DQ2.5 tag (rs2187668)	HLA autoimmune risk haplotype	not on this chip; not imputable with confidence
NOD2 R702W (Arg702Trp)	Crohn's / IBD gut-barrier risk	not on this chip; not imputable with confidence
NOD2 G908R (Gly908Arg)	Crohn's / IBD gut-barrier risk	not on this chip; not imputable with confidence

Training and recovery4 not read

Marker	What it is about	Why it was not read
ACE I/D (Alu indel)	endurance and power	an insertion or deletion — not on arrays
PPARGC1A Gly482Ser	aerobic capacity / mitochondrial	not on this chip; not imputable with confidence
COL5A1 rs12722 (3'-UTR)	tendon/ligament flexibility & injury risk	not on this chip; not imputable with confidence
AMPD1 Gln12Ter (Q12X)	exertional fatigue tolerance	not on this chip; not imputable with confidence

Blood tests on file

LDL

3.1 mmol/L2022-02-14
2.8 mmol/L2023-11-06
3.4 mmol/L2025-05-19lab range < 3

HbA1c

5.3 %2025-05-19

None on file: Total cholesterol, HDL, Triglycerides, CRP, Fasting glucose, Vitamin D, Homocysteine, Vitamin B12, Ferritin, ApoB, Lp(a).